MiRNA-145-5p inhibits gastric cancer progression via the serpin family E member 1- extracellular signal-regulated kinase-1/2 axis

doi:10.4251/wjgo.v16.i5.2123

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. May 15, 2024; 16(5): 2123-2140
Published online May 15, 2024. doi: 10.4251/wjgo.v16.i5.2123

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Figure 6 Effects of serpin family E member 1 overexpression on gastric cancer cell proliferation, invasion, migration, and apoptosis. A: Serpin family E member 1 (SERPINE1) mRNA and protein expression in lentivirus transfected SGC7901 cells; B: SERPINE1 overexpression promotes SGC7901 cell proliferation; C: SERPINE1 overexpression promotes SGC7901 cell colony formation; D: SERPINE1 promotes SGC7901 cell invasion; scale bar = 100 μm; E: SERPINE1 promotes SGC7901 cell migration; scale bar = 100 μm; F: SERPINE1 overexpression reduces SGC7901 cell apoposis. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001.

Citation: Bai HX, Qiu XM, Xu CH, Guo JQ. MiRNA-145-5p inhibits gastric cancer progression via the serpin family E member 1- extracellular signal-regulated kinase-1/2 axis. World J Gastrointest Oncol 2024; 16(5): 2123-2140
URL: https://www.wjgnet.com/1948-5204/full/v16/i5/2123.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i5.2123