SERPINH1 promoted the proliferation and metastasis of colorectal cancer by activating PI3K/Akt/mTOR signaling pathway

Figure 5 The effect of serpin peptidase inhibitor clade H member 1 on phosphatidylinositol 3-kinase/AKT/mechanistic target of rapamycin and phosphatidylinositol 3-kinase/AKT/FOXO1 signaling pathways. A: The protein-protein interaction network of serpin peptidase inhibitor clade H member 1 (SERPINH1); B and C: The expression of SERPINH1 is positively correlated to the AKT/FOXO1 of colorectal adenocarcinoma; D and E: Immunofluorescent staining of AKT and FOXO1 in HCT116 cells. SERPINH1: Serpin peptidase inhibitor clade H member 1.