Plexin domain-containing 1 may be a biomarker of poor prognosis in hepatocellular carcinoma patients, may mediate immune evasion

doi:10.4251/wjgo.v16.i5.2091

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. May 15, 2024; 16(5): 2091-2112
Published online May 15, 2024. doi: 10.4251/wjgo.v16.i5.2091

Table 3 Oncogenic pathway parameters in “GSVA” R package enrichment analysis

GeneSet	NES	NOM P value	FDR q-value
WNT_SIGNALING_PATHWAY	1.91	0	0.0054
NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY	1.89	0	0.0057
NEUROTROPHIN_SIGNALING_PATHWAY	1.90	0	0.0058
MAPK_SIGNALING_PATHWAY	1.91	0	0.0061
JAK_STAT_SIGNALING_PATHWAY	1.85	0	0.0069
HEDGEHOG_SIGNALING_PATHWAY	1.87	0	0.0069
TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	1.84	0	0.0069
TGF_BETA_SIGNALING_PATHWAY	1.84	0	0.0070
CHEMOKINE_SIGNALING_PATHWAY	1.82	0	0.0079

FDR: False detection rate; NES: Normalized Enrichment Score; NOM: Nominal.

Citation: Tang MY, Shen X, Yuan RS, Li HY, Li XW, Jing YM, Zhang Y, Shen HH, Wang ZS, Zhou L, Yang YC, Wen HX, Su F. Plexin domain-containing 1 may be a biomarker of poor prognosis in hepatocellular carcinoma patients, may mediate immune evasion. World J Gastrointest Oncol 2024; 16(5): 2091-2112
URL: https://www.wjgnet.com/1948-5204/full/v16/i5/2091.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i5.2091