Diagnostic performance of dynamic contrast-enhanced magnetic resonance imaging parameters and serum tumor markers in rectal carcinoma prognosis

Table 4 Receiver operating characteristic curve analysis of various parameters

Diagnostic variable	AUC	95%CI	Cut-off	Sensitivity	Specificity	Youden index
T stage
CA19-9	0.773	0.684-0.863	23.63	53.23%	100.00%	53.23%
CA125	0.802	0.716-0.888	66.90	67.74%	90.48%	58.22%
DCE-MRI parameters + tumor markers	0.836	0.756-0.916	0.93	72.58%	95.24%	67.82%
Differentiation degree
CA19-9	0.834	0.758-0.909	27.49	81.82%	68.42%	50.24%
CA125	0.796	0.711-0.881	66.82	62.12%	89.47%	51.60%
DCE-MRI parameters + tumor markers	0.946	0.903-0.990	0.76	87.88%	97.37%	85.25%

AUC: Area under the curve; DCE-MRI: Dynamic contrast-enhanced magnetic resonance imaging; CA19-9: Carbohydrate antigen 19-9; CA125: Carbohydrate antigen 125.