Diagnostic performance of dynamic contrast-enhanced magnetic resonance imaging parameters and serum tumor markers in rectal carcinoma prognosis

Table 3 Receiver operating characteristic curve analysis of various parameters

Diagnostic variable	AUC	95%CI	Cut-off	Sensitivity	Specificity	Youden index
T stage
Ktrans	0.638	0.532-0.745	0.26	62.90%	59.52%	22.43%
Ve	0.695	0.595-0.794	0.45	40.32%	92.86%	33.18%
DCE-MRI parameters	0.742	0.646-0.837	0.68	53.23%	92.86%	46.08%
Differentiation degree
Ktrans	0.672	0.549-0.795	0.29	87.88%	57.90%	45.77%
Ve	0.725	0.626-0.824	0.49	75.76%	63.16%	38.92%
DCE-MRI parameters	0.769	0.677-0.861	0.35	78.79%	65.79%	44.58%

AUC: Area under the curve; Ktrans: Volume transfer constant; Ve: Extravascular extracellular volume fraction; DCE-MRI: Dynamic contrast-enhanced magnetic resonance imaging.