Construction of CDKN2A-related competitive endogenous RNA network and identification of GAS5 as a prognostic indicator for hepatocellular carcinoma

Figure 5 Construction and functional enrichment analysis of long noncoding RNA-miRNA-mRNA triple regulatory networks. The diamonds denote long noncoding RNAs (lncRNAs), ellipses denote miRNAs, rectangles denote mRNAs. A: Cytoplasmic/nuclear localization of growth arrest-specific 5; B: The lncRNA-miRNA-mRNA triple regulatory network in hepatocellular carcinoma. Red indicates upregulated, and blue represents downregulated; C: Top 15 score genes identified by maximum clique centrality algorithm; D: Functional enrichment analysis of the differentially expressed messenger RNAs (DEmRNAs) in the network; E: Interactive network of the DEmRNAs. RCI: Relative concentration index; GAS5: Growth arrest-specific 5.