Transcriptome sequencing reveals novel biomarkers and immune cell infiltration in esophageal tumorigenesis

doi:10.4251/wjgo.v16.i4.1500

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World Journal of Gastrointestinal Oncology

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1948-5204

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World J Gastrointest Oncol. Apr 15, 2024; 16(4): 1500-1513
Published online Apr 15, 2024. doi: 10.4251/wjgo.v16.i4.1500

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Figure 4 The immune infiltration pattern of the 4-nitroquinoline 1-oxide group compared to the normal group. A: Fraction of immune cell infiltration in 4-nitroquinoline 1-oxide (4NQO) carcinogenic intervention and normal (NOR) groups based on CIBERSORT algorithm; B-D: Expression of M0 (CD68) and M1 (CD80 and CD86) macrophage markers in NOR and 4NQO groups including low-grade intraepithelial neoplasia, high-grade intraepithelial neoplasia, and carcinoma. ^aP < 0.05. LGIN: Low-grade intraepithelial neoplasia; HGIN: High-grade intraepithelial neoplasia; CA: Carcinoma; NK: Natural killer.

Citation: Sun JR, Chen DM, Huang R, Wang RT, Jia LQ. Transcriptome sequencing reveals novel biomarkers and immune cell infiltration in esophageal tumorigenesis. World J Gastrointest Oncol 2024; 16(4): 1500-1513
URL: https://www.wjgnet.com/1948-5204/full/v16/i4/1500.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i4.1500