FAM53B promotes pancreatic ductal adenocarcinoma metastasis by regulating macrophage M2 polarization

doi:10.4251/wjgo.v16.i4.1479

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Apr 15, 2024; 16(4): 1479-1499
Published online Apr 15, 2024. doi: 10.4251/wjgo.v16.i4.1479

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Figure 7 FAM53B induces M2 polarization by activating the Src/FAK/p-Akt/IL-1β signaling pathway. A and B: FAM53B knockout in induced pancreatic ductal adenocarcinoma tumor-associated macrophages (TAMs); C and D: FAM53B knockout in PANC-1-induced pancreatic ductal adenocarcinoma TAMs.

Citation: Pei XZ, Cai M, Jiang DW, Chen SH, Wang QQ, Lu HM, Lu YF. FAM53B promotes pancreatic ductal adenocarcinoma metastasis by regulating macrophage M2 polarization. World J Gastrointest Oncol 2024; 16(4): 1479-1499
URL: https://www.wjgnet.com/1948-5204/full/v16/i4/1479.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i4.1479