Meta-Analysis
Copyright ©The Author(s) 2024.
World J Gastrointest Oncol. Apr 15, 2024; 16(4): 1626-1646
Published online Apr 15, 2024. doi: 10.4251/wjgo.v16.i4.1626
Table 5 The gastric cancer organoids construction rate from different subgroups
Subgroup
Successful cases
Number of total
Number of study
Success rate (%)
95%CI
P value
I2
Gender
Female1423467.031.1-95.70.3136.07
Male2247446.731.5-62.2
Tissue source
Endoscopic biopsy1632353.727.1-79.50.2837.35
Surgery and ESD2840470.949.8-88.7
Differentiate type
Poor2743364.646.0-81.30.10642.54
Moderate515231.06.3-61.3
SRCC616432.70.6-76.7
pTNM
I-II38238.34.1-79.10.10842.54
III-IV182865.245.7-82.7
Enzyme
Liberase TH, TrypLE4767271.559.3-82.30.0469.27
EDTA, DL-dithiothreitol3468150.037.6-62.4
Collagenase3046372.144.4-93.6
Growth factor
B27103152368.746.9-83.30.9490.53
Non-B275577369.545.2-87.8
N-acetylcysteine111162471.938.2-96.20.9590.52
Non-N-acetylcysteine4767271.559.3-82.3
Gastrin111162471.938.2-96.20.9590.53
Non-gastrin4767271.559.3-82.3
FGF-293134367.421.6-99.20.9890.53
Non-FGF-26595367.949.2-84.2
Nutlin-34767271.559.3-82.30.9590.53
Non-nutlin-3111162471.938.2-96.2
Y-276322136258.241.6-75.00.50590.53
Non-Y-27632137193470.039.8-93.3