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©The Author(s) 2024.
World J Gastrointest Oncol. Apr 15, 2024; 16(4): 1421-1436
Published online Apr 15, 2024. doi: 10.4251/wjgo.v16.i4.1421
Published online Apr 15, 2024. doi: 10.4251/wjgo.v16.i4.1421
Table 1 Basic information of patients and its relationship with nicotinamide adenine dinucleotide phosphate oxidase 4
| Factor | Category | Total | High NOX4 (N = 52) | Low NOX4 (N = 30) | P value |
| Age (yr) | 64.46 ± 12.6 | 64.79 ± 12.38 | 63.9 ± 13.18 | 0.765 | |
| Gender | Female | 49 (60) | 31 (60) | 18 (60) | 1.000 |
| Male | 33 (40) | 21 (40) | 12 (40) | ||
| Tumor location | Left colon or rectum | 51 (62) | 35 (67) | 16 (53) | 0.307 |
| Right colon | 31 (38) | 17 (33) | 14 (47) | ||
| Histopathology | Well differentiated | 31 (38) | 17 (33) | 14 (47) | 0.373 |
| Moderately differentiated | 32 (39) | 23 (44) | 9 (30) | ||
| Poorly differentiated | 19 (23) | 12 (23) | 7 (23) | ||
| pT | T1 | 17 (21) | 11 (21) | 6 (20) | 0.357 |
| T2 | 26 (32) | 13 (25) | 13 (43) | ||
| T3 | 24 (29) | 17 (33) | 7 (23) | ||
| T4 | 15 (18) | 11 (21) | 4 (13) | ||
| pN | N0 | 45 (55) | 25 (48) | 20 (67) | 0.233 |
| N1 | 26 (32) | 18 (35) | 8 (27) | ||
| N2 | 11 (13) | 9 (17) | 2 (7) | ||
| pM | M0 | 82 (100) | 52 (100) | 30 (100) | 1.000 |
| M1 | 0 | 0 | 0 | ||
| pStage | Stage I | 19 (23) | 5 (10) | 14 (47) | < 0.001 |
| Stage II | 24 (29) | 19 (37) | 5 (17) | ||
| Stage III | 39 (48) | 28 (54) | 11 (37) |
- Citation: Xu YJ, Huo YC, Zhao QT, Liu JY, Tian YJ, Yang LL, Zhang Y. NOX4 promotes tumor progression through the MAPK-MEK1/2-ERK1/2 axis in colorectal cancer. World J Gastrointest Oncol 2024; 16(4): 1421-1436
- URL: https://www.wjgnet.com/1948-5204/full/v16/i4/1421.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v16.i4.1421