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©The Author(s) 2024.
World J Gastrointest Oncol. Apr 15, 2024; 16(4): 1296-1308
Published online Apr 15, 2024. doi: 10.4251/wjgo.v16.i4.1296
Published online Apr 15, 2024. doi: 10.4251/wjgo.v16.i4.1296
Table 2 The computed tomography features of gastrointestinal stromal tumor patients included in this study, n (%)
| Characteristics | KIT exon 11 mutation (n = 192) | Without KIT exon 11 mutation (n = 39) | P value | KIT exon 11 mutation with deletions involving codons 557-558 (n = 56) | KIT exon 11 mutation without deletions involving codons 557-558 (n = 136) | P value |
| Size (mm) | 51 (11-224) | 45 (10-201) | 0.682 | 69 (31-224) | 42.5 (11-188) | < 0.010 |
| Shape | ||||||
| Regular | 66 (34.4) | 7 (17.9) | 0.044 | 5 (8.9) | 61 (44.9) | < 0.010 |
| Irregular | 126 (65.6) | 32 (82.1) | 51 (91.1) | 75 (55.1) | ||
| Margin | ||||||
| Well-defined | 168 (87.5) | 23 (84.6) | 0.625 | 44 (78.6) | 124 (91.2) | 0.016 |
| Ill-defined | 24 (12.5) | 6 (15.4) | 12 (21.4) | 12 (8.8) | ||
| Growth pattern | ||||||
| Endophytic | 64 (33.3) | 6 (15.4) | 0.083 | 12 (21.4) | 52 (38.2) | 0.010 |
| Exophytic | 87 (45.3) | 22 (56.4) | 25 (44.6) | 62 (45.6) | ||
| Mixed | 41 (21.4) | 11 (28.2) | 19 (33.9) | 22 (16.2) | ||
| Density | ||||||
| Hypodensity | 175 (91.1) | 34 (87.2) | 0.647 | 50 (89.3) | 125 (91.9) | 0.750 |
| Isodensity | 15 (7.8) | 4 (10.3) | 5 (8.9) | 10 (7.4) | ||
| Hyperdensity | 2 (1.0) | 1 (2.6) | 1 (1.8) | 1 (0.7) | ||
| Pattern of enhancement | ||||||
| Homogeneous | 48 (25.0) | 5 (12.8) | 0.099 | 5 (8.9) | 43 (31.6) | 0.001 |
| Heterogeneous | 144 (75.0) | 34 (87.2) | 51 (91.1) | 93 (68.4) | ||
| Degree of enhancement | ||||||
| Mild | 71 (37.0) | 11 (28.2) | 0.018 | 20 (35.7) | 51 (37.5) | 0.063 |
| Moderate | 75 (39.1) | 10 (25.6) | 28 (50.0) | 47 (34.6) | ||
| Marked | 46 (24.0) | 18 (46.2) | 8 (14.3) | 38 (27.9) | ||
| Necrosis | 121 (63.0) | 28 (71.8) | 0.296 | 43 (76.8) | 78 (57.4) | 0.011 |
| Gas | 33 (17.2) | 4 (10.3) | 0.282 | 14 (25.0) | 19 (14.0) | 0.066 |
| Cystic change | 6 (3.1) | 4 (10.3) | 0.046 | 0 (0) | 6 (4.4) | 0.110 |
| Calcification | 23 (12.0) | 2 (5.1) | 0.209 | 8 (14.3) | 15 (11.0) | 0.528 |
| Superficial ulceration | 55 (28.6) | 10 (25.6) | 0.704 | 19 (33.9) | 36 (26.5) | 0.299 |
| Intra-tumoral vessel | 86 (44.8) | 14 (35.9) | 0.307 | 34 (60.7) | 52 (38.2) | 0.004 |
| Adjacent mesangial fat infiltration | 40 (20.8) | 9 (23.1) | 0.755 | 20 (35.7) | 20 (14.7) | 0.001 |
| Adjacent organ invasion | 29 (15.1) | 7 (17.9) | 0.655 | 14 (25.0) | 15 (11.0) | 0.014 |
| Lymphadenopathy | 14 (7.3) | 3 (7.7) | 0.930 | 6 (10.7) | 8 (5.9) | 0.242 |
| Distant metastasis | 4 (2.1) | 2 (5.1) | 0.276 | 3 (5.4) | 1 (0.7) | 0.042 |
- Citation: Yin XN, Wang ZH, Zou L, Yang CW, Shen CY, Liu BK, Yin Y, Liu XJ, Zhang B. Computed tomography radiogenomics: A potential tool for prediction of molecular subtypes in gastric stromal tumor. World J Gastrointest Oncol 2024; 16(4): 1296-1308
- URL: https://www.wjgnet.com/1948-5204/full/v16/i4/1296.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v16.i4.1296