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World J Gastrointest Oncol. Apr 15, 2024; 16(4): 1166-1179
Published online Apr 15, 2024. doi: 10.4251/wjgo.v16.i4.1166
Table 1 Classification of neuroendocrine component according to morphology, mitoses, and differentiation
Neuroendocrine component
Mitotic index
Ki-67
NET G1Mitotic index < 2 per 10 high-power fieldKi-67 < 3%
NET G2Mitotic index 2-20 high-power fieldKi-67 3%-20%
NET G3Mitotic index > 20 high-power fieldKi-67 > 20%
Poorly differentiated neuroendocrine cancersMitotic index > 20 high-power fieldKi-67 > 20%