Verteporfin fluorescence in antineoplastic-treated pancreatic cancer cells found concentrated in mitochondria

Figure 5 Fluorescence imaging of gemcitabine-treated AsPC-1 and BxPC-3 cells after staining. A and B: After treating (A) AsPC-1 and (B) BxPC-3 cells with 30 μmol/L gemcitabine for 72 h, the cells were incubated with 1 μmol/L verteporfin for 2 h, and then co-stained with MitoTracker Green and 4’,6-diamidino-2-phenylindole. The distribution of verteporfin in cells was carefully observed by confocal laser microscope. Experiments were performed in triplicate. MTG: MitoTracker Green; DAPI: 4’,6-diamidino-2-phenylindole.