Expression and significance of pigment epithelium-derived factor and vascular endothelial growth factor in colorectal adenoma and cancer

Figure 5 The relationship between the expression of pigment epithelium-derived factors and vascular endothelial growth factors with clinical parameters in colorectal cancer group. A: The relationship between positive expression rate of pigment epithelium-derived factors (PEDF) and age, gender, tumor size, and tumor location in colorectal cancer (CRC) group; B: The relationship between high expression rate of vascular endothelial growth factors (VEGF) and age, gender, tumor size, and tumor location in CRC group; C: The relationship between positive expression rate of PEDF and tumor differentiation, serous membrane infiltration, lymph node metastasis, remote metastasis and staging tumors in CRC group; D: The relationship between high expression rate of VEGF and tumor differentiation, serous membrane infiltration, lymph node metastasis, remote metastasis and staging tumors in CRC group. High expression: +++; Low expression: -~++; n = 50 (CRC group), NS: P ≥ 0.05. PEDF: Pigment epithelium-derived factors; VEGF: Vascular endothelial growth factors.