Clinical profile and outcomes of hepatocellular carcinoma in primary Budd-Chiari syndrome

Table 4 Management of patients with Budd-Chiari syndrome-hepatocellular carcinoma at follow-up

Age	Sex	Site of obstruction	Length of block	BCS intervention	BCS: Restenosis	BCS: Time between intervention and stent block in d	No. of reinterventions for BCS	Time between BCS and HCC diagnosis in d	AFP	BCLC	CTP	Initial HCC management	HCC response	Survival after diagnosis of HCC until last follow-up in d	No. of lesion/size	Reintervention for HCC
20	M	IVC + HV	Long	Medical management	No			2374	1320.0	B	B	TACE	PD	456	2.0 (3.0 cm × 3.6 cm)	2 (PAI, TACE)
35	F	IVC	Short	IVC angioplasty	Yes	1411	1 (IVC angioplasty)	2396	8.8	B	A	TACE	CR	3061	3.0 (2.9 cm × 2.5 cm)	-
40	M	IVC + HV	Long	Medical management	No			186	8489.0	B	A	SC	NA	5731	3 (6 cm × 7 cm)	-
52	M	HV	Long	HV angioplasty	Yes	116	1 (RHV stenting)	2148	4.0	B	B	TACE	CR	5241	2 (9 cm × 5 cm)	-
35	F	IVC	Long	IVC angioplasty	No			4273	3888.0	B	A	TACE	PD	1471	7.0 (4.0 cm × 3.9 cm)	-
47	F	IVC + HV	Long	IVC angioplasty	Yes	169	2 (IVC angioplasty, IVC angioplasty)	788	1240.0	B	A	TACE	PR	39281	3 (7 cm × 7 cm)	5 (TACE, TACE, PAI, TACE, TACE)
24	M	IVC + HV	Short	Medical management	No			3771	177910.0	D	C	SC	NA	58	Infiltrative	-
21	M	HV	Long	TIPSS	Yes	166	1 (TIPSS revision)	424	4.4	B	A	TACE	CR	23741	Multiple (3.1 cm × 2.3 cm)	-
22	F	IVC	Long	IVC angioplasty	Yes	973	2 (TIPSS, TIPSS revision)	2062	1300.0	C	B	TACE	NA	241	1 (11.2 cm × 8.8 cm)	-
45	F	IVC + HV	Long	IVC angioplasty	Yes	412	2 (Balloon dilatation, balloon)	4603	500.0	B	A	SC	NA	61	Multiple/NA	-
26	F	IVC + HV	Long	IVC angioplasty	No			4018	315.0	C	B	TKI	NA	2164	Infiltrative	-
52	F	IVC + HV	Long	IVC angioplasty	Yes	284	1 (IVC angioplasty)	1768	14951.0	D	C	SC	NA	401	Multiple	-
30	M	HV	Short	HV angioplasty	No			306	66.6	B	A	TACE	CR	1352	4.0 (4.1 cm × 3.6 cm)	2 (TACE, TACE)
40	M	IVC + HV	Long	IVC angioplasty	No			262	131.0	D	C	SC	NA	35	Infiltrative with PVT	-
32	F	IVC	Short	IVC angioplasty	No			3762	2.2	A	A	SC	NA	491	2 (2 cm × 1 cm)	-
30	M	IVC + HV	Long	PSRS	Yes	5484	1 (TIPSS)	5599	353.0	B	B	TACE	PR	171	2.0 (4.0 cm × 4.2 cm)	TKI
28	M	HV	Long	TIPSS	No			4023	500.0	D	C	SC	NA	221	Infiltrative with PVT	-

¹Alive at last follow-up. AFP: Alpha-fetoprotein; BCLC: Barcelona Clinic Liver Cancer; BCS: Budd-Chiari syndrome; CR: Complete response; CTP: Child Turcotte Pugh; F: Female; HCC: Hepatocellular carcinoma; HV: Hepatic vein; IVC: Inferior vena cava; M: Male; NA: Not available; PAI: Percutaneous acetic acid injection; PD: Progressive disease; PR: Partial response; PSRS: Proximal splenorenal shunts; PVT: Portal vein thrombosis; RHV: Right hepatic vein; SC: Supportive care; TACE: Transarterial chemoembolization; TIPSS: Transjugular intrahepatic portosystemic shunt; TKI: Tyrosine kinase inhibitor.