Impact of Alcian blue and periodic acid Schiff expression on the prognosis of gastric signet ring cell carcinoma

Table 1 Correlation between periodic acid Schiff expression and clinicopathologic features (n = 83), n (%)

Factors	Total	PAS		P value
	n = 83	≤ 50% positive	> 50% positive
Age (yr)				0.583
≤ 60	63 (75.9)	24 (72.7)	39 (78.0)
> 60	20 (24.1)	9 (27.3)	11 (22.0)
Gender				0.898
Male	32 (38.6)	13 (39.4)	19 (38.0)
Female	51 (61.4)	20 (60.6)	31 (62.0)
Tumor diameter				0.347
≤ 3	43 (51.8)	15 (45.5)	28 (56.0)
> 3	40 (48.2)	18 (54.5)	22 (44.0)
Vessel carcinoma embolus				0.608
No	33 (39.8)	12 (36.4)	21 (42.0)
Yes	50 (60.2)	21 (63.6)	29 (58.0)
Lymph node metastasis				0.331
Negative	33 (39.8)	11 (33.3)	22 (44.0)
Positive	50 (60.2)	22 (66.7)	28 (56.0)
Tumor stage				0.006
Early	21 (25.3)	3 (9.1)	18 (36.0)
Advanced	62 (74.7)	30 (90.9)	32 (64.0)
Ki67				0.394
≤ 50%	62 (74.7)	23 (69.7)	39 (78.0)
> 50%	21 (25.3)	10 (30.3)	11 (22.0)
P53				0.281
Negative	31 (37.3)	10 (30.3)	21 (42.0)
Positive	52 (62.7)	23 (69.7)	29 (58.0)
HER2				0.283
Negative	63 (75.9)	23 (69.7)	40 (80.0)
Positive	20 (24.1)	10 (30.3)	10 (20.0)

P < 0.05 is considered statistically significant. HER2: Human epidermal growth factor receptor 2; P53: Protein 53; PAS: Periodic acid-Schiff.