Early results of the integrative epigenomic-transcriptomic landscape of colorectal adenoma and cancer

doi:10.4251/wjgo.v16.i2.414

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Feb 15, 2024; 16(2): 414-435
Published online Feb 15, 2024. doi: 10.4251/wjgo.v16.i2.414

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Figure 3 Chromatin landscape of adenoma and colorectal cancer methylation alterations. A: Heatmap of histone mark enrichment at adenoma (ADE) differentially methylated positions (DMPs); B: Heatmap of the enrichment of 18 states of chromatin at ADE DMPs; C: Heatmap of histone mark enrichment at colorectal cancer (CRC) DMPs; D: Heatmap of the enrichment of 18 states of chromatin at CRC DMPs; E: Bubble plots showing enrichment locations of repetitive DNA classes; F: Barplots showing the relative numbers of transcription factors at the genomic locations of ADE and CRC DMPs. Only the top 50 most significantly enriched factors from each set were selected.

Citation: Lu YW, Ding ZL, Mao R, Zhao GG, He YQ, Li XL, Liu J. Early results of the integrative epigenomic-transcriptomic landscape of colorectal adenoma and cancer. World J Gastrointest Oncol 2024; 16(2): 414-435
URL: https://www.wjgnet.com/1948-5204/full/v16/i2/414.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i2.414