Preoperative controlling nutritional status as an optimal prognostic nutritional index to predict the outcome for colorectal cancer

Table 2 Clinicopathological characteristics of 217 patients with colorectal cancer after surgery

Variable	All (217)	The CONUT score		P value
		CONUT low (189)	CONUT high (28)
Age (yr)	58.4 ± 12.7	58.4 ± 12.4	58.9 ± 15.1	0.842
Male sex, n (%)	125 (57.6)	113 (59.8)	12 (42.9)	0.091
BMI (kg/m2)	22.9 ± 3.2	23.1 ± 3.1	21.5 ± 3.9	0.015
Tumor site, n (%)				0.787
Colon	122 (56.2)	105 (55.6)	17 (60.7)
Rectum	95 (43.8)	84 (44.4)	11 (39.3)
Comorbidities, yes, n (%)	69(31.8)	60(31.7)	9(32.1)	0.966
Sarcopenia, yes, n (%)	49 (22.6)	32 (16.9)	17 (60.7)	< 0.01
WBC (× 109/L)	5.84 ± 1.92	5.92 ± 1.92	5.27 ± 1.86	0.093
Platelet (× 109/L)	218 ± 85	222 ± 89	191 ± 46	0.068
Hemoglobin (g/L)	122.5 ± 24.6	125.6 ± 23.2	101.6 ± 24.1	< 0.01
Albumin (g/L)	41.3 ± 4.4	42.1 ± 3.7	35.7 ± 4.5	< 0.01
Lymphocyte (× 109/L)	1.6 ± 0.7	1.7 ± 0.6	0.9 ± 0.3	< 0.01
Cholesterol (mg/dL)	166.6 ± 41.5	173.0 ± 39.2	123.7 ± 30.0	< 0.01
CRP (mg/L)	8.9 ± 20.3	7.5 ± 19.7	18.5 ± 21.9	0.007
CEA (ng/ml)	5.9 ± 10.1	5.9 ± 10.5	6.6 ± 7.1	0.706
CA199 (U/ml)	25.5 ± 55.4	25.7 ± 56.8	24.5 ± 45.6	0.920
Postoperative complications, yes, n (%)	34 (15.7)	26 (13.8)	8 (28.6)	0.044
TNM stage, n (%)				0.044
Ⅰ	36 (6.6)	35 (18.5)	1 (3.6)
Ⅱ	91 (1.9)	74 (39.2)	17 (60.7)
Ⅲ	90 (41.5)	80 (42.3)	10 (35.7)

CONUT: Controlling nutritional status; BMI: Body mass index; WBC: White blood cell; CEA: Carcinoembryonic antigen; CA199: Carbohydrate antigen199; CRP: C-reactive protein.