Matrine promotes colorectal cancer apoptosis by downregulating shank-associated RH domain interactor expression

Figure 3 The expression of shank-associated RH domain interactor, metalloproteinase inhibitor 1, nucleolar complex protein 2 homolog, and DNA ligase 4 proteins and its association with tumor-node-metastasis and overall survival in colorectal cancer. A: The expression of 4 proteins among tumor-node-metastasis (TNM) stages in 52 colorectal cancer (CRC) patients; B: The expression of 4 proteins in TCGA; C: The expression of 4 proteins among TNM stages in TCGA; D: The association between expression of 4 proteins and overall survival in TCGA; E: The immunohistochemistry of shank-associated RH domain interactor in 93 CRC tissues and 35 normal tissues. ^aP < 0.05; ^bP < 0.01; CRC: Colorectal cancer; HC: Health control; SHARPIN: Shank-associated RH domain interactor; TIMP1: Metalloproteinase inhibitor 1; NOC2 L: Nucleolar complex protein 2 homolog; LIG4: DNA ligase 4.