Local excision for middle-low rectal cancer after neoadjuvant chemoradiation: A retrospective study from a single tertiary center

Table 4 Patients with disease progression after local excision

Patient (sex/age)	Primary staging				NCRT	Interval time (week)	Response		Disease progression			Prognosis
	cT	cN	cM	High-risk factor (s)			mrTRG	ypT	Local recurrence	Distant metastasis	Treatment	DFS (month)	OS (month)	Status
Male/74	T4	N1	cM0	cT4	NCRT	8.7	0	ypT0	Negative	Bone	C	9.3	64.6	Dead
Female/57	T3	N2	cM0	EMVI+	NCRT + CapOx2	9	0	ypT0	Negative	Lung	C+ resection	27.5	76.5	Alive (NED)
Female /61	T2	N2	cM0	N2	NCRT	101	3	ypT0	Positive	Sacrum and Lung	Resection	6.1	49.4	Dead
Female /36	T4	N1	cM1	cT4	CRT + CapOx2	19	2	ypT2	Negative	Lung	C+ resection		42.0	Alive (NED)
Female /30	T4	N2	cM1	cT4	CRT+CapOx1	36	1	ypT0	Positive	Liver	Resection		27.5	Alive (NED)

NCRT: Neoadjuvant chemoradiotherapy; EMVI: Extramural venous invasion; DFS: Disease-free survival; OS: Overall survival; NED: No evidence of disease; CapOx: Capecitabine + oxaliplatin.