Prognostic utility of gamma-glutamyl transpeptidase to platelet ratio in patients with solitary hepatitis B virus-related hepatocellular carcinoma after hepatectomy

Table 4 Stratified analysis between gamma-glutamyl transpeptidase-to-platelet ratio levels and prognosis in the solitary hepatitis B virus-related hepatocellular carcinoma

Variables	Before propensity matching				After propensity matching
	OS-HR (95%CI)	P value	RFS-HR (95%CI)	P value	OS-HR (95%CI)	P value	RFS-HR (95%CI)	P value
As continuous	1.12 (1.04-1.20)	0.002	1.11 (1.06-1.17)	< 0.001	1.29 (1.18-1.42)	< 0.001	1.20 (1.11-1.31)	< 0.001
By GPR cut-off
GPR ≤ 0.2
GPR > 0.2	2.07 (1.56-2.74)	< 0.001	2.05 (1.68-2.51)	< 0.001	2.04 (1.46-2.84)	< 0.001	1.79 (1.40-2.28)	< 0.001
By GPR tercile
Bottom (≤ 0.2)
Middle (> 0.2, ≤ 0.6)	1.81 (1.35-2.44)	< 0.001	1.85 (1.50-2.29)	< 0.001	1.52 (1.08-2.14)	0.017	1.69 (1.25-2.17)	< 0.001
Top (> 0.6)	2.74 (1.98-3.81)	< 0.001	2.60 (2.04-3.31)	< 0.001	2.33 (1.60-3.39)	< 0.001	2.35 (1.77-3.13)	< 0.001
P for trend1	< 0.001		< 0.001		< 0.001		< 0.001
By interquartile
Q1
Q2	1.42 (0.98-2.06)	0.061	1.43 (1.10-1.86)	< 0.001	0.75 (0.43-1.28)	0.288	0.88 (0.60-1.29)	0.514
Q3	1.72 (1.20-2.46)	0.003	1.74 (1.35-2.24)	< 0.001	1.45 (0.90-2.34)	0.125	1.58 (1.12-2.23)	0.009
Q4	2.34 (1.66-3.29)	< 0.001	2.29 (1.79-2.93)	< 0.001	2.08 (1.33-3.24)	0.001	1.79 (1.27-2.51)	0.001
P for trend1	< 0.001		< 0.001		< 0.001		< 0.001

¹Test for trend based on variable containing median value for each classification.

HR: Hazard ratio; OS: Overall survival; RFS: Recurrence-free survival; GPR: Gamma-glutamyl transpeptidase-to-platelet ratio.