BIRC3 induces the phosphoinositide 3-kinase-Akt pathway activation to promote trastuzumab resistance in human epidermal growth factor receptor 2-positive gastric cancer

Figure 3 Expression of BIRC3 in human gastric cancer cell lines and trastuzul resistant cell lines. A: mRNA levels of BIRC3 in NCI-N87, and NCI-N87R cells were examined by reverse transcription polymerase chain reaction; GAPDH was used as a control; B: Protein levels of BIRC3 in NCI-N87, and NCI-N87R cells were examined by western blotting, β-actin was a negative control. ^aP < 0.001; ^bP < 0.0001.