Effect of colorectal cancer stem cells on the development and metastasis of colorectal cancer

Figure 4 Lipid metabolism in protumor immune responses. STAT3: Signal transducer and activator of transcription 3; CPT1B: Carnitine palmitoyltransferase 1B; FAO: Fatty acid oxidation; PD-1: Programmed cell death protein 1; PPAR: Peroxisome proliferator-activated receptor; MSR1: Macrophage scavenger receptor 1; TGFBR1: Transforming growth factor beta receptor 1; TLR: Toll-like receptor; mTOR: Mechanistic target of rapamycin; DC: Dendritic cell; MDSC: Myeloid-derived suppressor cell; NK: Natural killer; FATP: Fatty acid transport protein; Arg: Arginine; IL: Interleukin; TNF: Tumor necrosis factor; ABCG1: ATP-binding cassette sub-family G member 1; ROS: Reactive oxygen species; iNOS: Inducible nitric oxide synthase; CXCR: C-X-C chemokine receptor; ATGL: Adipose triglyceride lipase; PGE2: Prostaglandin E2; PUSFA: Polyunsaturated fatty acids; M-CSF: Macrophage colony-stimulating factor; TGF: Transforming growth factor; Treg: Regulatory T cell.