Copyright
©The Author(s) 2024.
World J Gastrointest Oncol. Nov 15, 2024; 16(11): 4338-4353
Published online Nov 15, 2024. doi: 10.4251/wjgo.v16.i11.4338
Published online Nov 15, 2024. doi: 10.4251/wjgo.v16.i11.4338
Figure 1 MET mutations.
MET mutations include point mutations, insertion mutations, amplification and other types. Common mutation sites are mainly concentrated in tyrosine kinase domains (such as Exon 14 hops) and extracellular domains, which lead to abnormal activation of MET signaling pathway.
- Citation: Zhang C, Dong HK, Gao JM, Zeng QQ, Qiu JT, Wang JJ. Advances in the diagnosis and treatment of MET-variant digestive tract tumors. World J Gastrointest Oncol 2024; 16(11): 4338-4353
- URL: https://www.wjgnet.com/1948-5204/full/v16/i11/4338.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v16.i11.4338