Letter to the Editor
Copyright ©The Author(s) 2024.
World J Gastrointest Oncol. Nov 15, 2024; 16(11): 4522-4527
Published online Nov 15, 2024. doi: 10.4251/wjgo.v16.i11.4522
Table 2 Clinical relevance of the association between neutrophil-to-lymphocyte ratio, hemoglobin, and colorectal cancer prognosis
Parameter
High NLR
Low Hb
Clinical associated factorsHigher secretion of chemokines and inflammatory cytokinesAnemia and iron losses (bleeding, ingestion and absorption deficiency)
Clinical outcomesSuppression of apoptosis, increased proliferation, migration, and invasion of tumor cells, and organ dysfunctionReduced erythropoiesis, low iron release, cachexia
Number of patients admitted with CRC-PM (poor prognosis)40.6% (54/133)70.6% (94/133)