Clinical significance of upregulated Rho GTPase activating protein 12 causing resistance to tyrosine kinase inhibitors in hepatocellular carcinoma

Figure 10  Potential regulatory mechanisms of Rho GTPase activating protein 12. A: Intersection of tyrosine kinase inhibitor-resistant genes, upregulated differentially expressed genes from bulk high-throughput data, and Rho GTPase activating protein 12 positively correlated genes; B: Enrichment analysis; C: Intersection of genes in the focal adhesion pathway from single-cell RNA sequencing and bulk RNA data. TKI: Tyrosine kinase inhibitor.