Clinical significance of upregulated Rho GTPase activating protein 12 causing resistance to tyrosine kinase inhibitors in hepatocellular carcinoma

doi:10.4251/wjgo.v16.i10.4244

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Oct 15, 2024; 16(10): 4244-4263
Published online Oct 15, 2024. doi: 10.4251/wjgo.v16.i10.4244

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Figure 5 Analysis of the MK communication network. A: Heatmap of outgoing and incoming signal patterns; B: Ligand-receptor network of MK signaling; C: Heatmap plot of MDK-(integrin alpha 6 + integrin β-1) expression. ITGA6: Integrin alpha 6; ITGB1: Integrin β-1; FA: Focal adhesion.

Citation: Wang XW, Tang YX, Li FX, Wang JL, Yao GP, Zeng DT, Tang YL, Chi BT, Su QY, Huang LQ, Qin DY, Chen G, Feng ZB, He RQ. Clinical significance of upregulated Rho GTPase activating protein 12 causing resistance to tyrosine kinase inhibitors in hepatocellular carcinoma. World J Gastrointest Oncol 2024; 16(10): 4244-4263
URL: https://www.wjgnet.com/1948-5204/full/v16/i10/4244.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i10.4244