Intratumoural microorganism can affect the progression of hepatocellular carcinoma

Figure 6 Propionibacterium and propionic acid repressed in vivo hepatocellular carcinoma tumorigenesis. A: Tumor formation in mice implanted with subcutaneous tumor after 2 weeks. The mice showed varying degrees of emaciation; B: Subcutaneous tumors after dissection; C: The subcutaneous tumor volume in control group was significantly higher than that in Propionibacterium group; D: Liver orthotopic implantation model was administered two weeks later; E: Tumor size of hepatocellular carcinoma in orthotopic model. ^aP < 0.05.