Jianpi-Huatan-Huoxue-Anshen formula ameliorates gastrointestinal inflammation and microecological imbalance in chemotherapy-treated mice transplanted with H22 hepatocellular carcinoma

Figure 3 Effects of Tzu-Chi cancer-antagonizing & life-protecting II decoction on serum IL-1β, IL-6, IL-8, IL-22, IL-10, TNF-α, and TGF-β and intestinal SIgA in chemotherapy-treated H22 hepatocellular carcinoma mice. A-G: Contents of serum IL-1β (A), IL-6 (B), IL-8 (C), IL-10 (D), IL-22 (E), TNF-α(F), and TGF-β (G); H: Intestinal SIgA content. Data with error bars are represented as the mean ± SD (n = 6 or 7). ^aP < 0.05 vs NS-Contr; ^bP < 0.01 vs NS-Contr; ^cP < 0.05 vs 5-fluorouracil (FU)-Contr; ^dP < 0.01 vs 5-FU-Contr, one-way ANOVA. 5-FU: 5-fluorouracil; YZXJ: Yangzhengxiaoji capsules; TCCL-H: High-dose Tzu-Chi cancer-antagonizing & life-protecting II decoction; TCCL-M: Medium-dose Tzu-Chi cancer-antagonizing & life-protecting II decoction; TCCL-L: Low-dose Tzu-Chi cancer-antagonizing & life-protecting II decoction.