Long noncoding RNA steroid receptor RNA activator 1 inhibits proliferation and glycolysis of esophageal squamous cell carcinoma

Figure 1 Steroid receptor RNA activator 1 expression level was decreased in human esophageal squamous cell carcinoma tissues and cell lines. A: The five pairs of esophageal squamous cell carcinoma (ESCC) and adjacent normal tissues were carried out long non-coding RNA (LncRNA) microarray analysis, and the lncRNA expression patterns were performed through hierarchical clustering; B: Changes in the lncRNA level were displayed in the volcano plot; C: LncRNA SRA1 had the highest fold of differential expression; D: Steroid receptor RNA activator 1 (SRA1) expression was apparently downregulated in ESCC tissues; E: SRA1 expression was apparently downregulated in ESCC cell line; F: ESCC patients with low SRA1 expression had shorter overall survival than patients with high SRA1 expression. ^aP < 0.01; ^bP < 0.05 vs Het-1A; ^cP < 0.01 vs Het-1A; LncRNA: Long non-coding RNA; SRA1: Steroid receptor RNA activator 1.