Characteristics and risk factor analyses of high-grade intraepithelial neoplasia in older patients with colorectal polyps

doi:10.4251/wjgo.v16.i10.4129

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Oct 15, 2024 (publication date) through Feb 5, 2025

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World Journal of Gastrointestinal Oncology

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1948-5204

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World J Gastrointest Oncol. Oct 15, 2024; 16(10): 4129-4137
Published online Oct 15, 2024. doi: 10.4251/wjgo.v16.i10.4129

Table 4 The proportion of patients with elevated serum tumor markers in the high-grade intraepithelial neoplasia group and low-grade intraepithelial neoplasia group, n (%)

Tumor marker	HGIN group (number of cases = 84)	LGIN group (number of cases = 112)	χ²	P value
CEA			6.212	0.013
Ascension	17 (20.24)	9 (8.04)
Normal	67 (79.76)	103 (91.96)
CA724			3.519	0.061
Ascension	6 (7.14)	2 (1.79)
Normal	78 (92.86)	110 (98.21)
CA199			13.259	0.000
Ascension	15 (17.86)	3 (2.68)
Normal	69 (82.14)	109 (97.32)
CA242			2.890	0.089
Ascension	4 (4.76)	1 (0.89)
Normal	80 (95.24)	111 (99.11)

LGIN: Low-grade intraepithelial neoplasia; HGIN: High-grade intraepithelial neoplasia; CA199: Cancer antigen 199; CA724: Cancer antigen 724; CA242: Cancer antigen 242; CEA: Carcinoembryonic antigen.

Citation: Zhang X, Wang Y, Zhu T, Ge J, Yuan JH. Characteristics and risk factor analyses of high-grade intraepithelial neoplasia in older patients with colorectal polyps. World J Gastrointest Oncol 2024; 16(10): 4129-4137
URL: https://www.wjgnet.com/1948-5204/full/v16/i10/4129.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i10.4129