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©The Author(s) 2024.
World J Gastrointest Oncol. Oct 15, 2024; 16(10): 4092-4103
Published online Oct 15, 2024. doi: 10.4251/wjgo.v16.i10.4092
Published online Oct 15, 2024. doi: 10.4251/wjgo.v16.i10.4092
Table 3 Cox regression analysis for factors affecting the 3-year survival of intrahepatic cholangiocarcinoma in 141 patients enrolled in cohorts
Variable | No. of participants (n = 141) | Univariate analysis HR (95%CI) | P value | Multivariate analysis HR (95%CI) | P value |
Tumor necrosis | 0.01 | 0.03 | |||
0 | 50 | 1 | 1 | ||
0.5 | 6 | 1.31 (1.03, 1.62) | 1.26 (1.13, 1.41) | ||
1 | 85 | 1.93 (1.20, 3.12) | 1.73 (1.06, 2.84) | ||
Tumor metastasis | < 0.001 | 0.008 | |||
No | 20 | 1 | 0.47 (0.27, 0.82) | ||
Yes | 121 | 2.53 (1.48, 4.32) | 1 | ||
Child-Pugh | 0.001 | < 0.001 | |||
Group A | 136 | 1 | 0.17 (0.07, 0.46) | ||
Group B | 5 | 4.49 (1.80, 11.22) | 1 | ||
CD20 | 0.03 | - | |||
High | 61 | 1 | |||
Low | 80 | 1.65 (1.06, 2.58) | |||
Paired adjacent tissues CD20 | 0.74 | - | |||
High | 83 | 1 | |||
Low | 58 | 1.48 (0.96, 2.26) | |||
CD4 | 0.09 | - | |||
High | 16 | 1 | |||
Low | 125 | 2.04 (0.89, 4.69) | |||
Paired adjacent tissues CD4 | 0.15 | 0.02 | |||
High | 100 | 1 | 2.01 (1.13, 3.57) | ||
Low | 41 | 0.70 (0.43, 1.14) | 1 | ||
CD8 | 0.16 | - | |||
High | 73 | 1 | |||
Low | 68 | 1.35 (0.88, 2.07) | |||
Paired adjacent tissues CD8 | 0.01 | < 0.001 | |||
High | 84 | 1 | 0.4 (0.25, 0.67) | ||
Low | 57 | 1.75 (1.15, 2.68) | 1 | ||
CK | 0.01 | 0.04 | |||
High | 112 | 1 | 0.58 (0.35, 0.96) | ||
Low | 29 | 1.86 (1.15, 3.02) | 1 | ||
Paired adjacent tissues CK | 0.16 | - | |||
High | 104 | 1 | |||
Low | 37 | 1.39 (0.88, 2.19) | |||
CD68 | 0.30 | - | |||
High | 113 | 1 | |||
Low | 28 | 0.74 (0.42, 1.31) | |||
Paired adjacent tissues CD68 | 0.35 | - | |||
High | 130 | 1 | |||
Low | 11 | 0.65 (0.26, 1.60) |
- Citation: Wang ZR, Zhang CZ, Ding Z, Li YZ, Yin JH, Li N. Establishing prognostic models for intrahepatic cholangiocarcinoma based on immune cells. World J Gastrointest Oncol 2024; 16(10): 4092-4103
- URL: https://www.wjgnet.com/1948-5204/full/v16/i10/4092.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v16.i10.4092