Mechanism of pachymic acid in the treatment of gastric cancer based on network pharmacology and experimental verification

Figure 6 Effect of pachymic acid on the expression of PI3K/AKT pathway and apoptosis-related proteins in gastric cancer cell line HGC-27. A and B: The impact of pachymic acid (PA) on the expression of proteins connected to the PI3K/AKT signaling pathway in HGC-27 cells; C and D: The impact of PA on the expression of apoptosis-related proteins in HGC-27 cells. All experiments were repeated three times and the data were expressed as mean ± SD, ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. NC: Negative control; PA: Pachymic acid.