Copyright
©The Author(s) 2024.
World J Gastrointest Oncol. Jan 15, 2024; 16(1): 30-50
Published online Jan 15, 2024. doi: 10.4251/wjgo.v16.i1.30
Published online Jan 15, 2024. doi: 10.4251/wjgo.v16.i1.30
Figure 4 Analysis of molecular docking and clinical relevance.
A: Pachymic acid docked with the top 6 core target molecules with degree value; B: Copy number analysis of the top ten core targets in gastric cancer (GC); C: Correlation analysis between GC and paracancerous sites of the top ten core targets; D: GC grading and staging analysis of the top ten core targets; E: Survival analysis of the top ten core targets. SRC: Proto-oncogene tyrosine-protein kinase Src; MAPK1: Mitogen-activated protein kinase 1; PI3KR1: Phosphatidylinositol 3-kinase regulatory subunit alpha; HSP90AA1: Heat shock protein 90-alpha; PTPN11: Tyrosine-protein phosphatase non-receptor type 11; GRB2: Growth factor receptor-bound protein 2; RXRA: Retinoic acid receptor RXR-alpha; MAPK14: Mitogen-activated protein kinase 14; EGFR: Epidermal growth factor receptor; ESR1: Estrogen receptor.
- Citation: Du YH, Zhao JJ, Li X, Huang SC, Ning N, Chen GQ, Yang Y, Nan Y, Yuan L. Mechanism of pachymic acid in the treatment of gastric cancer based on network pharmacology and experimental verification. World J Gastrointest Oncol 2024; 16(1): 30-50
- URL: https://www.wjgnet.com/1948-5204/full/v16/i1/30.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v16.i1.30