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©The Author(s) 2023.
World J Gastrointest Oncol. Sep 15, 2023; 15(9): 1520-1530
Published online Sep 15, 2023. doi: 10.4251/wjgo.v15.i9.1520
Published online Sep 15, 2023. doi: 10.4251/wjgo.v15.i9.1520
Figure 2 Metastasis-associated lung adenocarcinoma transcript 1 expression is influenced by protein CCL21.
Metastasis-associated lung adenocarcinoma transcript 1 sponges miR-202-3p, then SRSF1 mRNA (serine and arginine-rich splicing factor 1) is translated in protein and activates mammalian target of rapamycin pathway improving epithelial-mesenchymal transition (EMT) factors and decreasing E-cadherin expression. EMT: epithelial-mesenchymal transition; MALAT1: Metastasis-associated lung adenocarcinoma transcript 1; SRSF1: serine and arginine-rich splicing factor 1; mTOR: Mammalian target of rapamycin.
- Citation: Batista DMO, da Silva JMC, Gigek CO, Smith MAC, de Assumpção PP, Calcagno DQ. Metastasis-associated lung adenocarcinoma transcript 1 molecular mechanisms in gastric cancer progression. World J Gastrointest Oncol 2023; 15(9): 1520-1530
- URL: https://www.wjgnet.com/1948-5204/full/v15/i9/1520.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v15.i9.1520