Metastasis-associated lung adenocarcinoma transcript 1 molecular mechanisms in gastric cancer progression

Figure 1 Metastasis-associated lung adenocarcinoma transcript 1 subcellular location. A: Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is the red strand around the nuclear spots (white spheres), MALAT1 can interact with proteins present in nuclear speckles; B: MALAT1 can interact with serine/arginine proteins to modulate alternative splicing of pre-mRNAs; C: MALAT1 binds with transcriptional enhancer factor transcriptional enhanced factors with TEA/ATTS domain, blocking Yes-associated protein, inhibiting gene transcription. MALAT1: Metastasis-associated lung adenocarcinoma transcript 1; SR: Serine/arginine-rich; TEAD: Transcriptional enhanced factors with TEA/ATTS domain; YAP: Yes-associated protein.