Factors associated with heterochronic gastric cancer development post-endoscopic mucosal dissection in early gastric cancer patients

Table 5 Univariate analysis of risk factors for the development of heterochronic gastric cancer

Clinicopathological features	OR	95%CI	P value
Age ≥ 65 yr	7.571	1.606-35.699	0.004
Male	5.400	1.146-25.446	0.022
Smoking (BI ≥ 400)	3.441	1.056-11.214	0.074
Family history of stomach cancer	5.111	0.774-33.752	0.123
Initial multiple foci	1.813	0.344-9.560	0.831
Lesion ≥ 2 cm	1.167	0.407-3.344	0.794
Lesion in the lower third of the stomach	7.778	1.690-35.795	0.034
O-shaped atrophy	3.437	0.924-12.784	0.061
Severe intestinalization	3.821	1.234-11.828	0.047
Divergent	9.375	1.192-73.735	0.037
Depth of submucosal infiltration < 500 μm	1.320	0.144-12.089	0.585

95%CI: 95% confidence interval; OR: Odds ratio; BI: Brinkman index.