RNA-binding protein CPSF6 regulates IBSP to affect pyroptosis in gastric cancer

doi:10.4251/wjgo.v15.i9.1531

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

World J Gastrointest Oncol. Sep 15, 2023; 15(9): 1531-1543
Published online Sep 15, 2023. doi: 10.4251/wjgo.v15.i9.1531

Table 1 Correlation between integrin binding sialoprotein expression and clinicopathologic characteristics in gastric cancer patients

Parameter	n	Low IBSP expression (n = 8)	High IBSP expression (n = 22)	P value
Age (yr)
≥ 60	11	4	7	0.361
< 60	19	4	15
Tumor diameter (cm)
≥ 3	10	6	4	0.004^a
< 3	20	2	18
Gender
Male	14	3	11	0.544
Female	16	5	11
TNM stage
I + II	7	5	2	0.002^a
III + IV	23	3	20
Distant metastasis
M0	15	5	10	0.409
M1	15	3	12

^aP < 0.05 was considered to have a significant difference.

Categorical variables were compared by the chi-square test. IBSP: Integrin binding sialoprotein.

Citation: Wang XJ, Liu Y, Ke B, Zhang L, Liang H. RNA-binding protein CPSF6 regulates IBSP to affect pyroptosis in gastric cancer. World J Gastrointest Oncol 2023; 15(9): 1531-1543
URL: https://www.wjgnet.com/1948-5204/full/v15/i9/1531.htm
DOI: https://dx.doi.org/10.4251/wjgo.v15.i9.1531