LINC01268 promotes epithelial-mesenchymal transition, invasion and metastasis of gastric cancer via the PI3K/Akt signaling pathway and targeting MARCKS

Figure 6 Comparison of the invasion and migration ability of gastric cancer cells after down-regulation of LINC01268. A: The invasive ability of MGC80-3 in the sh-LINC01268 group was significantly weaker than that in the sh-negative control (sh-NC) group; B: The migration ability of MGC80-3 in the sh-LINC01268 group was significantly weaker than that in the sh-NC group; C: The invasive ability of AGS in the sh-LINC01268 group was significantly weaker than that in the sh-NC group; D: The migration ability of AGS in the sh-LINC01268 group was significantly weaker than that in the sh-NC group; E: After knocking down the expression of LINC01268 in MGC80-3, the cell migration ability was significantly weakened; F: After knocking down the expression of LINC01268 in AGS, the cell migration ability was significantly weakened. All the experiments were performed in triplicate. The results were shown as the mean ± SD. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. sh-NC: sh-negative control.