LINC01268 promotes epithelial-mesenchymal transition, invasion and metastasis of gastric cancer via the PI3K/Akt signaling pathway and targeting MARCKS

Figure 1 Relative expression level of LINC01268 in gastric cancer. A: The relative expression level of LINC01268 in 62 cases of gastric cancer (GC) tissues was higher than that of adjacent noncancerous tissues (ANTs). Expression levels were normalized to ACTB levels; B: The expression level of LINC01268 was up-regulated in 39 GC tissues and down-regulated in 23 GC tissues [bars represent the ratio between the expression levels in GC tissues and ANTs (C/N, log scale) from the 62 patients]; C: The relative expression levels of LINC01268 in GC cell lines MGC80-3 and AGS were higher than those in normal gastric mucosa epithelial cell line GES-1. Expression levels were normalized to GAPDH levels. The results were shown as the mean ± SD. ^bP < 0.01, ^dP < 0.0001. GC: Gastric cancer; ANT: Adjacent noncancerous tissue.