Carcinoembryonic antigen, carbohydrate antigen 199 and carbohydrate antigen 724 in gastric cancer and their relationship with clinical prognosis

Table 6 Relationship between serum carcinoembryonic antigen, carbohydrate antigen 199 and carbohydrate antigen 724 levels and clinicopathology in patients with gastric cancer

Clinical pathology		n	CEA (ng/mL)	CA199 (U/mL)	CA724 (U/mL)
Gender	Male	46	23.42 ± 4.65	52.49 ± 7.83	41.29 ± 6.18
	Female	41	23.99 ± 5.12	53.04 ± 7.67	41.35 ± 6.22
Age	< 45 years old	60	20.47 ± 8.53	49.18 ± 9.13	39.02 ± 6.45
	≥ 45 years old	27	30.85 ± 8.77a	60.68 ± 8.85a	46.43 ± 6.76a
Smoking history	Yes	52	23.51 ± 4.43	52.66 ± 8.41	41.57 ± 6.17
	No	35	23.96 ± 4.50	52.88 ± 8.35	40.95 ± 6.03
Alcohol history	Yes	56	23.49 ± 4.81	52.69 ± 7.41	41.30 ± 5.94
	No	31	24.05 ± 4.87	52.86 ± 9.03	41.36 ± 6.12
TNM staging	Phase I-II	43	21.02 ± 4.65	48.63 ± 8.75	37.25 ± 6.88
	Phase III-IV	44	26.30 ± 4.72b	56.78 ± 9.24b	45.30 ± 7.13b
lymphatic metastasis	No	45	20.83 ± 4.23	46.16 ± 7.36	38.11 ± 6.59
	Yes	42	26.75 ± 4.88c	59.81 ± 8.48c	44.76 ± 6.13c
Tumor diameter	< 5 cm	49	19.61 ± 4.67	47.02 ± 8.55	35.26 ± 6.62
	≥ 5 cm	38	28.95 ± 5.01d	60.14 ± 9.31d	49.13 ± 6.89d

^aP < 0.05, compared with age < 45 years.

^bP < 0.05, compared with TNM stage I-II.

^cP < 0.05, compared with no lymph node metastasis.

^dP < 0.05, compared with tumor diameter < 5 cm.

CEA: Carcinoembryonic antigen; CA199: Carbohydrate antigen 199; CA724: Carbohydrate antigen 724.