Retrospective Cohort Study
Copyright ©The Author(s) 2023.
World J Gastrointest Oncol. Aug 15, 2023; 15(8): 1436-1450
Published online Aug 15, 2023. doi: 10.4251/wjgo.v15.i8.1436
Table 1 Comparison of clinicopathological characteristics between gallbladder mucinous adenocarcinoma and typical gallbladder adenocarcinoma before and after propensity score matching, n (%)
CharacteristicUnmatched cohort (n = 4711)
Propensity score-matched cohort (n = 374)
GBMAC (n = 187)
Typical GBAC (n = 4524)
P value
GBMAC (n = 187)
Typical GBAC (n = 187)
P value
Age (yr)0.9550.373
< 6043 (23.0)1061 (23.5)43 (23.0)35 (18.7)
≥ 60144 (77.0)3463 (76.5)144 (77.0)152 (81.3)
Sex0.6380.064
Female 127 (67.9)3158 (69.8)127 (67.9)144 (77.0)
Male60 (32.1)1366 (30.2)60 (32.1)43 (23.0)
Race0.2570.467
White133 (71.1)3373 (74.6)133 (71.1)128 (68.4)
Black34 (18.2)610 (13.5)34 (18.2)39 (20.9)
Others20 (10.7)523 (11.6)20 (10.7)18 (9.6)
Unknown0 (0.0)18 (0.4)0 (0.0)2 (1.1)
Marital status0.0240.758
Married78 (41.7)2239 (49.5)78 (41.7)71 (38.0)
Unmarried105 (56.1)2101 (46.4)105 (56.1)112 (59.9)
Unknown4 (2.1)184 (4.1)4 (2.1)4 (2.1)
Grade0.5670.613
Well differentiated24 (12.8)462 (10.2)24 (12.8)18 (9.6)
Moderately differentiated60 (32.1)1465 (32.4)60 (32.1)56 (29.9)
Poorly differentiated48 (25.7)1285 (28.4)48 (25.7)48 (25.7)
Undifferentiated0 (0.0)29 (0.6)0 (0.0)1 (0.5)
Unknown55 (29.4)1283 (28.4)55 (29.4)64 (34.2)
Surgery0.8850.107
Yes127 (67.9)3000 (66.3)127 (67.9)111 (59.4)
No60 (32.1)1523 (33.7)60 (32.1)76 (40.6)
Unknown0 (0.0)1 (0.0)
Chemotherapy0.3691
Yes90 (48.1)2014 (44.5)90 (48.1)90 (48.1)
No/Unknown97 (51.9)2510 (55.5)97 (51.9)97 (51.9)
Radiotherapy0.2111
Yes32 (17.1)616 (13.6)32 (17.1)32 (17.1)
No/Unknown155 (82.9)3908 (86.4)155 (82.9)155 (82.9)
AJCC0.0050.226
I4 (2.1)335 (7.4)4 (2.1)11 (5.9)
II26 (13.9)867 (19.2)26 (13.9)19 (10.2)
III62 (33.2)1215 (26.9)62 (33.2)62 (33.2)
IV95 (50.8)2107 (46.6)95 (50.8)95 (50.8)
T stage0.0060.435
T110 (5.3)507 (11.2)10 (5.3)19 (10.2)
T250 (26.7)1394 (30.8)50 (26.7)42 (22.5)
T387 (46.5)1808 (40.0)87 (46.5)88 (47.1)
T418 (9.6)242 (5.3)18 (9.6)15 (8.0)
Unknown22 (11.8)573 (12.7)22 (11.8)23 (12.3)
N stage0.0130.312
N092 (49.2)2673 (59.1)92 (49.2)107 (57.2)
N165 (34.8)1138 (25.2)65 (34.8)49 (26.2)
N211 (5.9)336 (7.4)11 (5.9)13 (7.0)
Unknown19 (10.2)377 (8.3)19 (10.2)18 (9.6)
M stage0.6681
M0102 (54.5)2613 (57.8)102 (54.5)102 (54.5)
M185 (45.5)1910 (42.2)85 (45.5)85 (45.5)
Unknown0 (0.0)1 (0.0)