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©The Author(s) 2023.
World J Gastrointest Oncol. Aug 15, 2023; 15(8): 1366-1383
Published online Aug 15, 2023. doi: 10.4251/wjgo.v15.i8.1366
Published online Aug 15, 2023. doi: 10.4251/wjgo.v15.i8.1366
Characteristics | No. of each group | LINC01268 expression | P value | |
High | Low | |||
All cases | 62 | 39 | 23 | |
Age (yr) | ||||
≥ 60 | 38 | 23 | 15 | 0.626 |
< 60 | 24 | 16 | 8 | |
Gender | ||||
Male | 53 | 32 | 21 | 0.531 |
Female | 9 | 7 | 2 | |
Smoking | ||||
Yes | 23 | 15 | 8 | 0.772 |
No | 39 | 24 | 15 | |
Drinking alcohol | ||||
Yes | 21 | 14 | 7 | 0.661 |
No | 41 | 25 | 16 | |
Maximum tumor diameter | ||||
≥ 5 | 25 | 19 | 6 | 0.079 |
< 5 | 37 | 20 | 17 | |
Depth of invasion | ||||
pT1-pT2 | 8 | 5 | 3 | 1.000 |
pT3-pT4 | 54 | 34 | 20 | |
Lymph node metastasis | ||||
pN0 | 10 | 2 | 8 | 0.007 |
pN1-pN3 | 52 | 37 | 15 | |
Distant metastasis | ||||
pM0 | 59 | 36 | 23 | 0.453 |
pM1 | 3 | 3 | 0 | |
Tumor TNM stage | ||||
I-II | 12 | 4 | 8 | 0.043 |
III-IV | 50 | 35 | 15 | |
Histology | ||||
Middle differentiated and well differentiated | 23 | 10 | 13 | 0.015 |
Poor differentiated | 39 | 29 | 10 | |
Macroscopic types | ||||
Mass | 3 | 0 | 3 | 0.378 |
Ulcerative | 12 | 8 | 4 | |
Infiltrative ulcerative | 47 | 31 | 16 | |
Diffuse infiltrative | 0 | 0 | 0 | |
Venous/lymphatic invasion | ||||
Positive | 10 | 7 | 3 | 0.881 |
Negative | 52 | 32 | 20 | |
Nervous invasion | ||||
Positive | 7 | 5 | 2 | 0.936 |
Negative | 55 | 34 | 21 | |
Fatty nodules | ||||
Positive | 8 | 7 | 1 | 0.250 |
Negative | 54 | 32 | 22 | |
Liver metastasis | ||||
Present | 3 | 2 | 1 | 1.000 |
Absent | 59 | 37 | 22 | |
Ascitic fluid | ||||
Negative | 48 | 30 | 18 | 0.903 |
Positive | 14 | 9 | 5 |
- Citation: Tang LH, Ye PC, Yao L, Luo YJ, Tan W, Xiang WP, Liu ZL, Tan L, Xiao JW. LINC01268 promotes epithelial-mesenchymal transition, invasion and metastasis of gastric cancer via the PI3K/Akt signaling pathway and targeting MARCKS. World J Gastrointest Oncol 2023; 15(8): 1366-1383
- URL: https://www.wjgnet.com/1948-5204/full/v15/i8/1366.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v15.i8.1366