Transcription factor glucocorticoid modulatory element-binding protein 1 promotes hepatocellular carcinoma progression by activating Yes-associate protein 1

Figure 2 Biological functions of glucocorticoid modulatory element-binding protein 1 in hepatocellular carcinoma. A: Western blotting was utilized to detect glucocorticoid modulatory element-binding protein 1 (GMEB1) expression in HepG2 cells transfected with GMEB1 overexpression plasmids and Huh7 cells transfected with si-GMEB1#1 and si-GMEB1#2; B: Evaluation of cell proliferation by the CCK-8 method; C and D: Detection of cell apoptosis via flow cytometry. E and F: Transwell assays were carried out to detect cell migration; G and H: Transwell assays were carried out to detect cell invasion. ^bP < 0.01; and ^eP < 0.001. GMEB1: Glucocorticoid modulatory element-binding protein 1; YAP1: Yes-associate protein 1.