BZD9L1 benzimidazole analogue hampers colorectal tumor progression by impeding angiogenesis

Figure 4 Analyses of mouse choroidal endothelial sprouts in sprouting and regression models. A: BZD9L1 impeded mouse choroidal endothelial sprouting 96 h post-treatment; B: Regressed choroid sprouting 24 h post-treatment compared to the negative control. A receptor like type 1 anti-angiogenic agent was used as the positive control regression and sprouting assays. Statistical analysis (^aP < 0.05; ^cP < 0.001), one-way ANOVA with Bonferroni posthoc test, n = 2 independent experiments using GraphPad Prism 9.4.0. Error bars represent SEM. ALK1: A receptor like type 1; NC: Negative control.