Circ_0003356 suppresses gastric cancer growth through targeting the miR-668-3p/SOCS3 axis

Figure 7 Circ_0003356 upregulation impedes gastric cancer tumorigenesis in vivo. A: Representative images of tumor in xenograft mice; B: Average volumes of xenograft mice; C: Average tumor weights of xenograft mice; D: Expression of E-cadherin, N-cadherin, Ki67, and SOCS3 in tumor tissues of xenograft mice determined by immunohistochemical staining; E: TUNEL staining to detect cell apoptosis in tumor tissues of mice; F: Expression of circ_0003356 and miR-668-3p determined by quantitative real-time polymerase chain reaction in tumor tissues of mice. ^bP < 0.01, ^cP < 0.001.