Efficacy of image-enhanced endoscopy for colorectal adenoma detection: A multicenter, randomized trial

doi:10.4251/wjgo.v15.i5.878

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

World J Gastrointest Oncol. May 15, 2023; 15(5): 878-891
Published online May 15, 2023. doi: 10.4251/wjgo.v15.i5.878

Table 3 All polyps analysis of both group

	IEE group (n = 2113)	WLI group (n = 2098)	P value	Relative risk (95%CI)
PDR	882/2113 (41.7)	757/2098 (36.1)	0.01	1.16 (1.07-1.25)
All polyps	1588	1319
Inflammatory polyp	426 (26.8)	341 (25.9)	0.55	1.04 (0.92-1.17)
Hyperplastic polyp	179 (11.3)	150 (11.4)	0.93	0.99 (0.81-1.22)
Adenoma polyp	690 (43.5)	590 (44.7)	0.49	0.97 (0.90-1.06)
Sessile serrated adenoma	10 (0.6)	11 (0.8)	0.52	0.76 (0.32-1.77)
Chronic inflammation	262 (16.5)	211 (16.0)	0.71	1.03 (0.87-1.22)
Cancer	16 (1.0)	13 (1.0)	0.95	1.02 (0.49-2.12)
Others	5 (0.3)	3 (0.2)	0.74¹	1.38 (0.33-5.78)
Adenoma per colonoscopy	0.33 ± 0.68	0.28 ± 0.62	0.06
Adenoma polyp	690	590
Size			0.44
≤ 5 mm	338 (49.0)	294 (49.8)		0.98 (0.88-1.10)
6-9 mm	211 (30.6)	163 (27.6)		1.11 (0.93-1.32)
≥ 10 mm	141 (20.4)	133 (22.5)		0.91 (0.74-1.12)
Shape			0.39
Pedunculated	72 (10.4)	76 (12.9)		0.81 (0.60-1.10)
Subpedunculated	186 (27.0)	154 (26.1)		1.03 (0.86-1.24)
Flat	432 (62.6)	360 (61.0)		1.03 (0.94-1.12)
Pathology			0.80
Tubular adenoma	670 (97.1)	569 (96.4)		1.01 (0.99-1.03)
Tubulovillous adenoma	18 (2.6)	19 (3.2)		0.81 (0.43-1.53)
Villous adenoma	2 (0.3)	2 (0.3)		0.86 (0.12-6.05)
Site			0.50
Left	258 (37.4)	236 (40.0)		0.94 (0.81-1.07)
Right	357 (51.7)	299 (50.7)		1.02 (0.92-1.14)
Rectum	75 (10.9)	55 (9.3)		1.17 (0.84-1.62)

¹Using fisher exact test.

Others in image-enhanced endoscopy group: Dermatofibroma × 1, fibroepithelial polyp × 1, neuroendocrine tumor × 1, soft fibroma × 1, gland hyperplasia × 1. Others in white light imaging group: Neuroendocrine tumor × 1, lymphoid polyps × 1, inflammatory granulation tissue × 1. Dates are n or n (%). PDR: Polyp detection rate; IEE: Image-enhanced endoscopy; WLI: White light imaging; CI: Confidence interval.

Citation: Qi ZP, Xu EP, He DL, Wang Y, Chen BS, Dong XS, Shi Q, Cai SL, Guo Q, Li N, Li X, Huang HY, Li B, Sun D, Xu JG, Chen ZH, Yalikong A, Liu JY, Lv ZT, Xu JM, Zhou PH, Zhong YS. Efficacy of image-enhanced endoscopy for colorectal adenoma detection: A multicenter, randomized trial. World J Gastrointest Oncol 2023; 15(5): 878-891
URL: https://www.wjgnet.com/1948-5204/full/v15/i5/878.htm
DOI: https://dx.doi.org/10.4251/wjgo.v15.i5.878