Real-world 10-year retrospective study of the guidelines for diagnosis and treatment of primary liver cancer in China

Table 7 Analysis of factors influencing postoperative recurrence in patients with hepatocellular carcinoma

Variables	Univariate analysis	Multivariate analysis
	P value	P value	Hazard ratio (95%CI)
Sex	0.0455a	0.0164a	0.694 (0.515–0.935)
Age (> 50)	0.9711	—
Screening	0.0678	—
HBV	0.7773	—
HCV	0.3531	—
Child-Pugh grade	0.0012b	0.0016b	1.771 (1.243–2.524)
CNLC staging	< 0.001b
Early			1 reference
Middle		< 0.001b	2.556 (2.032–3.215)
Late		< 0.001b	3.312 (2.113-5.192)
AFP (ng/mL)	< 0.001b
≤ 20			1 reference
20–400		0.338	1.139 (0.873–1.487)
> 400		< 0.001b	1.612 (1.256–2.070)

^aP < 0.05.

^bP < 0.01.

CI: Confidence interval; HCC: Hepatocellular carcinoma; HBV: Hepatitis B virus; HCV: Hepatitis C virus; CNLC: China Liver Cancer staging; AFP: Alpha-fetoprotein.