Real-world 10-year retrospective study of the guidelines for diagnosis and treatment of primary liver cancer in China

doi:10.4251/wjgo.v15.i5.859

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May 15, 2023 (publication date) through Jan 10, 2025

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. May 15, 2023; 15(5): 859-877
Published online May 15, 2023. doi: 10.4251/wjgo.v15.i5.859

Table 3 Compliance with and effect of hepatocellular carcinoma screening, n (%)

Variable	Total (n = 3022)	Whether to undergo screening		χ²	P value
Variable	Total (n = 3022)	Yes, n = 304 (10.06%)	No, n = 2718 (89.94%)	χ²	P value
Sex				0.254	0.614
Male	2487 (82.30)	247 (81.25)	2240 (82.41)
Female	535 (17.70)	57 (18.75)	478 (17.59)
Age				0.621	0.431
< 50	884 (29.25)	83 (27.30)	801 (29.47)
≥ 50	2138 (70.75)	221 (72.70)	1917 (70.53)
Chronic hepatitis				1.891	0.595
HBV	2694 (89.15)	266 (87.50)	2428 (89.33)
HCV	142 (4.70)	19 (6.25)	123 (4.53)
Mix	45 (1.49)	5 (1.64)	40 (1.47)
None	141 (4.66)	14 (4.61)	127 (4.67)
Smoking				0.652	0.419
Yes	1158 (38.32)	110 (36.18)	1048 (38.56)
No	1864 (61.68)	194 (63.82)	1670 (61.44)
Alcohol				1.217	0.270
Yes	949 (31.40)	87 (28.62)	862 (31.71)
No	2073 (68.60)	217 (71.38)	1856 (68.29)
Hypertension				2.714	0.099
Yes	533 (17.64)	64 (21.05)	469 (17.26)
No	2489 (82.36)	240 (78.95)	2249 (82.74)
Diabetes				0.002	0.968
Yes	360 (11.91)	36 (11.84)	324 (11.92)
No	2662 (88.09)	268 (88.16)	2394 (88.08)
Coronary heart disease				3.559	0.059
Yes	95 (3.14)	15 (4.93)	80 (2.94)
No	2927 (96.86)	289 (95.07)	2638 (97.06)
Family history of tumors				0.009	0.923
Yes	473 (15.65)	47 (15.46)	426 (15.67)
No	2549 (84.35)	257 (84.54)	2292 (84.33)
AFP (ng/mL)				41.808	0.000^a
≤ 20	1094 (36.20)	145 (47.70)	949 (34.92)
20-400	757 (25.05)	93 (30.59)	664 (24.43)
> 400	1171 (38.75)	66 (21.71)	1105 (40.65)
Child-Pugh Grade				58.031	0.000^a
A	2191 (72.50)	276 (90.79)	1915 (70.46)
B	737 (24.39)	28 (9.21)	709 (26.09)
C	94 (3.11)	0 (0.00)	94 (3.45)
CNLC				183.202	0.000^a
Ia	620 (20.52)	141 (46.38)	479 (17.62)
Ιb	447 (14.79)	57 (18.75)	390 (14.35)
IIa	60 (1.99)	12 (3.95)	48 (1.77)
IIb	887 (29.35)	59 (19.41)	828 (30.46)
IIIa	552 (18.27)	27 (8.88)	525 (19.32)
IIIb	362 (11.98)	8 (2.63)	354 (13.02)
IV	94 (3.10)	0 (0.00)	94 (3.46)

^aP < 0.01.

HBV: Hepatitis B virus; HCV: Hepatitis C virus; Mix: HBV complicated with HCV; CNLC: China Liver Cancer staging; AFP: Alpha-fetoprotein.

Citation: Yan YW, Liu XK, Zhang SX, Tian QF. Real-world 10-year retrospective study of the guidelines for diagnosis and treatment of primary liver cancer in China. World J Gastrointest Oncol 2023; 15(5): 859-877
URL: https://www.wjgnet.com/1948-5204/full/v15/i5/859.htm
DOI: https://dx.doi.org/10.4251/wjgo.v15.i5.859