Possible mechanisms associated with immune escape and apoptosis on anti-hepatocellular carcinoma effect of Mu Ji Fang granules

Figure 4 Mu Ji Fang Granules improved average body weight, spleen and thymus indices, decreased the concentration of hepatocellular carcinoma indicators, liver function indicators and immune factors. A: Average body weight, spleen index and thymus index (n = 8); B: Concentrations of hepatocellular carcinoma indicator alpha-fetoprotein, liver function indicators alanine aminotransferase and aspartate aminotransferase and immune factors Tumor necrosis factor α, Interferon gamma and Interleukin-2 in serum (n = 8); C: Tumor tissue from H22 tumor-bearing mice and the tumor inhibitory rate (n = 8); D: Hematoxylin and eosin staining of tumor tissue pathology sections from H22 tumor-bearing mice (n = 3). Data are shown as the mean ± standard deviation. ^aP < 0.01 vs Blank. ^bP < 0.01 vs Model. ^cP < 0.05 vs Model. ^dP < 0.01 vs M-L. ^eP < 0.05 vs M-L.